7-Day Mississippi Itinerary

Theme: A mix of Southern history, Delta blues, riverfront towns, and Gulf Coast charm across Mississippi.

Best Time to Visit: Spring (March-May) or Fall (September-November) for mild weather.

Day 1: Arrive in Jackson & Explore

Fly into Jackson-Medgar Wiley Evers International Airport (JAN).

Top Things to Do in Jackson:

Visit the Mississippi Civil Rights Museum – A powerful and moving experience.

Explore the Mississippi Museum of Art.

Tour the Eudora Welty House & Garden – Home of the famous author.

Dinner at the Mayflower Cafe – A classic spot for Southern cuisine.

Overnight in Jackson.

Day 2: Natchez – Historic Riverfront & Antebellum Homes

Drive from Jackson to Natchez (1.5 hours).

Top Things to Do in Natchez:

Tour Longwood or Stanton Hall – Stunning antebellum mansions.

Walk the Natchez Bluff Trail – Beautiful views over the Mississippi River.

Drive the Natchez Trace Parkway – A historic and scenic route.

Dinner & Sunset Drinks at Magnolia Grill.

Overnight in Natchez.

Day 3: Vicksburg – Civil War History & River Views

Drive from Natchez to Vicksburg (1.5 hours).

Top Things to Do in Vicksburg:

Visit the Vicksburg National Military Park – A key Civil War battlefield.

Tour the Old Courthouse Museum – Full of Civil War artifacts.

Try Your Luck at Riverfront Casinos.

Eat at The Beechwood – A legendary local steakhouse.

Overnight in Vicksburg.

Day 4: The Mississippi Delta – Blues & Culture

Drive from Vicksburg to Clarksdale (2 hours).

Top Things to Do in Clarksdale:

Visit the Delta Blues Museum.

See the "Crossroads" Where Robert Johnson Allegedly Sold His Soul.

Lunch at Abe's BBQ – A Delta favorite since 1924.

Catch Live Blues at Red's Lounge or Ground Zero Blues Club.

Overnight in Clarksdale.

Day 5: Oxford – College Town & Literary History

Drive from Clarksdale to Oxford (1.5 hours).

Top Things to Do in Oxford:

Visit Rowan Oak – Home of William Faulkner.

Explore the Historic Oxford Square.

Enjoy Dinner at City Grocery.

Overnight in Oxford.

Day 6: Mississippi Gulf Coast – Biloxi & Ocean Springs

Drive from Oxford to Biloxi (5 hours).

Top Things to Do in Biloxi & Ocean Springs:

Relax on the White Sand Beaches.

Visit a Biloxi Casino Like Beau Rivage.

Tour the Ohr-O'Keefe Museum of Art.

Dinner at The Blind Tiger or Half Shell Oyster House.

Overnight in Biloxi or Ocean Springs.

Day 7: Gulf Islands National Seashore & Depart

Explore the Gulf Coast Before Heading Back.

Top Things to Do:

Take a Ferry to Ship Island.

Explore Davis Bayou in Gulf Islands National Seashore.

Fly out of Gulfport-Biloxi International Airport (GPT) or drive back to Jackson (3.5 hours).

Total Drive Time:

Approx. 15-20 hours of driving across Mississippi.